Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1552 | Steroid metabolism + action | ICEECE2012

Myostatin and Follistatin expression in orchidectomized rats submitted to exercise

Marine D. , Bueno P. , Silva R. , Selistre-Araujo H. , Nonaka K. , Leal A.

Myostatin (MSTN) is a negative regulator of skeletal muscle growth, while androgens are strong positive regulators of muscle growth and strength. Follistatin (FS) is a binding protein which inhibits MSTN action. Evidences suggest that MSTN and testosterone actions in muscle may be associated. However, the mechanisms of androgens actions are not fully elucidated. The objective of this study was to evaluate the influence of exercise training in the expression of MSTN and FS in o...